Chinese team successfully completes pig-to-human xenogeneic liver transplant

The reporter learned from the First Affiliated Hospital of Anhui Medical University that the team of Professor Sun Beicheng of the hospital and the team of Professor Wei Hongjiang of Yunnan Agricultural University successfully completed the world's first living human xenograft liver transplantation. This marks a major breakthrough for Chinese scientists in related medical fields.

This time, 10 gene-edited pigs were transplanted into the patient's liver. The patient was a 71-year-old patient with giant liver cancer in the right lobe. When interventional and other treatments were ineffective and rupture could occur at any time, after fully obtaining the informed consent of the family and the patient, the team will start from The liver of a 514-gram 10-gene-edited pig (11 months old, weight 32 kg, male) obtained from the Yunnan Provincial Key Laboratory of Miniature Pig Gene Editing and Xenotransplantation at Yunnan Agricultural University was transplanted into the patient's right liver fossa. The operation went very smoothly. , secrete bile immediately.

As of May 24, the seventh day after the operation, the patient was in good condition, could move freely, and his liver function had returned to normal.